Vacature PhD student experimental oncology
The AMC is more than just a hospital. It is a world in which patient care, research and education are integrated, and in which people are always central. It is an academic world full of possibilities for talented individuals that are looking for a place where they can excel. Thinking big, daring to dream, cooperating internationally. And never letting yourself be put off by ‘It's not possible' or 'It won't work anyway'. That is the AMC mentality.
AMC Medical Research supports financiers, project leaders and coworkers on clear, effective and Legal execution of medical research within the Academic Medical Center (AMC) third parties financed. It contains advising and guidance on project preparations, project services and staffing management.
We offer a position within the Laboratory of Experimental Oncology and Radiobiology (LEXOR) at the Academic Medical Center in Amsterdam. LEXOR encompasses an international team of more than 40 researchers that all focus on the biological aspects of gastrointestinal cancer. Cell biological approaches, primary cultures, animal models and clinical studies are conducted in order to address the mechanisms by which tumor cells develop and resist chemo- , radio- and targeted therapy in a highly competitive, international and stimulating environment.
Colorectal cancer is one of our main topics and we study the role of inter and intra-tumor heterogeneity on the resistance of cancers to chemotherapy. You will study the distinct subtypes in colorectal cancer and try to evaluate what determines the initiation of the subtypes and what pathways are crucial for their maintenance. In addition, you will try to expose their vulnerabilities. Together with several other PhD students and postdocs you will work on primary cancer models and xenografted tumor material to study the pathways that dictate the biological properties of the colorectal cancer subtypes and perform compound screens to determine the optimal treatment schedules. In addition, you will be involved in the study of organoid models from specific mouse strains to determine the origin of the subtypes and the influence of exogenous factors on the development of these cancers. The position is financed by the AMC and KWF and will be part of a team that consists of a Postdoc, two PhD students and a technician.
- You have a completed master degree;
- You are a pro-active team player with a strong ambition to succeed;
- You have a proven affinity with cancer research;
- You have experience with primary cell culture;
- Experience with animal experimentation is beneficial.
Salary and Benefits
Working at AMC means working in an inspiring and professional environment in which developing one`s talents and skills is encouraged. We offer a salary in line with the Collective Labour Agreement for University Medical Centers in the Netherlands (CAO UMC) with a range of added fringe benefits, such as an annual bonus of 8.3 %, holiday allowance, collective discounted rates for a number of insurances, an attractive public transport allowance and free parking!
The position is for a period of 4 years. The gross salary will be € 2.222,00 gross per month in the first year, increasing to EUR 2.846,00 in the final year. Appointment takes place at AMC Medical Research BV. Location will be AMC in Amsterdam.
If you wish to apply for this position, click on the 'solliciteren'' button. For questions about this vacancy, please contact: Prof dr Jan Paul Medema, firstname.lastname@example.org, tel: 020-5667777.
Applications sent directly to the contact person or otherwise, will not be processed.
We are looking forward to meeting you!
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